Gates is well aware that AI will change the way people work and do business, and that there will be job loss as a result.
Repetitive blue collar and physical jobs will be affected first, but that tasks that involve reading and writing fluency will also be impacted by AI(This is happening as of right now!).
This could open up new opportunities in the legal world, or in the processing invoices world, or in the medical world. Just like it is providing new opportunities and disruptive uses for search.