COVID-19 Vaccines That Are Likely To Be Given In India In 2021!

India is currently surviving the second India is currently surviving the second wave of COVID-19 that has put its healthcare system on the verge of being collapsed. People are facing a scarcity of essential medical supplies such as oxygen and many other necessary medicines.

It has led to the shortage of vaccines that has hindered the hope of getting protected from the disease. Looking at the current trends, the government is making all the efforts to turn things around by the end of 2021.

NITI Aayog released a detailed plan about the availability of eight COVID-19 vaccines that will roll out to push the vaccination drive. It can be considered a significant and much-needed push that will help India get vaccinated quickly and proceed further to the step of gaining herd immunity.

Current COVID-19 vaccines that are available in India

There are currently two COVID-19 vaccines in India, Astra-Zeneca Oxford Covishield and Bharat Biotech’s Covaxin, that are being administered at the vaccination drive. Soon Russian vaccine Sputnik-V will be available to speed up the vaccination process.

The centre has announced that between August and December, most of the citizens will get vaccinated.

What are those about eight COVID-19 vaccines that are likely to be available soon?

Covaxin

This vaccine is made in India by the Indian pharmaceutical firm Bharat biotech with the help of the National Institute of Virology and Indian Council Medical Research (ICMR). These vaccines are currently in use at many places in India.

Covaxin is 81% effective against the virus, according to reports, and can neutralize UK, Indian, and Brazilian strains. 

This vaccine has used the sample of deadly coronavirus with the help of the National Institute of Virology to make the anti-covid jab. It will make the human immune system detect the virus and will help in creating antibodies.

The Covaxin is currently being sold to the central government at Rs 150, while the state government is getting it at 400. Rs 1200 is the price set for any private institution. 

Covishield

Covishield is developed by Oxford–AstraZeneca and manufactured in the Serum Institute of India. It is one of the vaccines that is being used widely in India to push the vaccination drive.

Covishield vaccine is made from the weakened version adenovirus (common cold virus in chimpanzees) to develop antibodies in the human immune system against this virus.

Studies have shown Covishield has a 90% efficacy rate against the virus if the second dose of these vaccines is taken after two months from the first dose.

The Serum Institute of India is charging Rs 150 for the centre and Rs 450 for state governments. For private institutions, the price is set at Rs 700.

Sputnik V

The Gamaleya Institute in Moscow developed the Sputnik V vaccine. It employs a harmless cold-type virus as a courier to carry a small portion of the coronavirus to the body. 

Giving the tiny fragment of the virus to the body will help the immune system recognize the threat of this virus and provide time to form antibodies to fight against it without being at risk of falling ill. 

Sputnik V is likely to be available in India by this week.

Bharat Biotech Nasal Vaccine

This vaccine developed by Bharat Biotech is currently in its first phase of trials. Officials from the Ministry of Health said that by December, they expect to have procured ten crore doses of the Nasal Vaccine produced by Bharat Biotech.

This vaccine does not require a needle; hence people will have to go to their nearby healthcare provider to get this vaccine through nasal drops. The institute claims that it will be available for both children and adults.

Novavax

The COVID-19 vaccine, developed by the US pharmaceutical company Novavax, will be produced by the Serum Institute of India and marketed as Covovax.

This vaccine is yet to get approved in the United States, the United Kingdom, and India has shown 96.4 percent effectiveness against moderate to severe effects caused by the initial strain of SARS-CoV-2. It had an effectiveness of about 86.3 percent against mutant virus variants.

The vaccine is currently in its 2nd phase of trials.

Bio E SUBunit Vaccine

This vaccine is developed by the Hyderabad-based firm Biological E, and it’s expected to roll out its vaccine in August after phase 3 results. According to the Ministry Of Health And Family Welfare, Biological E will supply 30 crore doses of its vaccine between August and December.

The company claims to provide the most affordable vaccine in India.

Zydus Cadila DNA vaccine

This vaccine developed by an Ahmedabad-based firm is currently waiting for its 3rd phase results and is likely to start production by the end of May. It is another indigenously prepared vaccine after Covaxin.

The company plans to make one crore doses per month after the third phase results.

Gennova mRNA Vaccine

It is India’s first mRNA vaccine prepared by a Pune-based Pharmaceutical firm Gennova. The company expected to have a phase 1 trial soon to conduct human tests in December by DGCI. The firm is scheduled to get emergency use after the phase 2 results.

It is India’s first indigenously mRNA messenger vaccine after vaccines like Pfizer and Moderna, which are based on the same mRNA pattern.

As the cases are rising in India daily, it becomes crucial for people to get vaccinated as soon as possible. It is the only way to curb the spread of the virus and to attain immunity against it. If all approved, these eight COVID-19 vaccines will serve to develop antibodies against the virus and help speed up the vaccination drive.

Read inspiring and happy stories about COVID-19 warriors to brighten up your mood!

#COVID19: Why The Primary Outcome Of Any Trial Should Be Reported Before The Commencement?

Similarly, in clinical trials one starts with a target – aka primary endpoint. Generally this is the outcome of the trial you want to measure. These outcomes differ based on the kind of trial being planned. E.g. if we were planning a heart failure trial, some outcomes we might..
measure would be : improvement in LV function, improvement in symptom status, hospitalization, to just name a few. In Covid trials, these end points are determined based on the population we are studying, so for mild cases it might be time to recovery, or progression of disease.
For moderate to severe cases on the other hand, we tend to look at more serious endpoints like need for oxygen or mechanical ventilation or death. The outcome has to be relevant to the patient and it should easily measurable with limited scope for manipulation or bias.
“Composite end point of symptom relief AND free from oxygen on Day 3” might just be the only significant thing they could find when they analysed their 100 measurements, and given this language it sure sounds like it. We won’t know anyhow until they give us a preprint or publish.
Until then, take this press release with a HUGE truckload of salt. End of tweetorial
@drabbyphilips @PriyankaPulla @d_s_thakur @netshrink @swapneilparikh @Charakan @just1doctorwala @pash22 @Neurophysik @Sulci_Gyri @omlakhani


» NextBigWhat’s #Threadmill brings you curated wisdom from Twitter threads on product, life and growth.

Read more posts on #CovidWarriors and Social Enterprise here!

Vaccine for 18+ above: How to apply? All you need to know!

The second wave of Covid-19 is a deadly reminder that the battle against the virus is not over yet. Even though we are the largest vaccine producer in the world, we are far from being a vaccinated nation as a whole. The continuous surge in COVID-19 cases has forced the government to take some necessary actions in such situations. 

This includes the opening of a vaccination drive for all adults above the age of 18. This begins on May 1st, and registrations for the same starts from April 28 on the CoWin portal and the Arogya Setu App. 

Important Announcements by the Government

Apart from opening the vaccination drive for everyone above 18 years of age, the government also announced that other bodies like the state governments and private hospitals are allowed to approach the vaccine manufacturer directly. 

With the commencement of the third vaccination drive, the vaccine manufacturers will supply 50% of their lot to the central government. The rest 50% will be available for the open market, private hospitals and the state governments. 

The central government vaccination programme will continue as before for health professionals, frontline workers and citizens above 45 years of age. 

How to register for the COVID-19 vaccine on the CoWin platform?

  1. Visit www.cowin.gov.in.
  2. Click on Register/Sign In Yourself
  3. Enter your mobile number in the space provided, click get OTP.
  4. You will receive an OTP on your phone number. 
  5. Enter the received OTP and click “Verify”.
  6. The registration page for vaccination will open. Choose the photo ID proof you wish to upload.
  7. Fill in the necessary details like your name, age, and gender. Now upload an identity document.
  8. Click “Register”.
  9. Once you are done with registration, click on “Account Details”.
  10. Any registered citizen can choose to add three more people by clicking the “Add More” button. 
  11. Now click on the ‘Schedule appointment’ button to make an appointment.
  12. Depending on the choice of your state, district, block, and pin code, you can search a vaccination centre.
  13. The data and availability for the same vaccination centre will be displayed to you.
  14. Click ‘book’ to confirm the appointment. 
  15. Once confirmed, you will get a message with the necessary details. Show these details at the vaccination centre for verification. 

How to register for the COVID-19 vaccine on Arogya Setu App?

  1. Open Arogya Setu. If you don’t have it yet, you can download it from the Play Store. 
  2. On the homepage, tap on the ‘CoWIN’ tab.
  3. You will be able to see four options, namely – Vaccine Information, Vaccination, Vaccination Certificate, and Vaccination Dashboard.
  4. Select the “Vaccination” tab and then tap on “Register Now”.
  5. Enter your mobile number in the space provided and then tap “proceed to verify”.
  6. You’ll receive an OTP. Enter the same in the same provided and tap “proceed to verify” again.
  7. Once you’re done with mobile number verification, upload a photo ID card from your files.
  8. Fill in the necessary details like age, gender, year of birth.
  9. Unlike the CoWin portal, you can add four beneficiaries here.
  10. Depending on your choice of state, district, block, and pin code, the available vaccination sites will be displayed to you. 
  11. Choose any one that suits you the best and tap on the “Book” option.
  12. Once done, you will receive the necessary details through SMS. Show the same on the day of vaccination for verification.

[Get Realtime Information on Medicines, Oxygen in Your City/ Locality]

Many states have announced free vaccination for their people. States that are offering COVID-19 vaccine for free are:

  1. Karnataka
  2. Ladakh
  3. Delhi
  4. Odisha
  5. Uttarakhand
  6. Gujarat
  7. Rajasthan
  8. Maharashtra
  9. Assam
  10. Bihar
  11. Madhya Pradesh
  12. Sikkim

Which vaccines are available in the country?

Mainly two vaccines available to the citizens of the country right now. One is Covishield, which is developed and marketed by Serum Institute of India. The other one is Covaxin, which has been developed by Bharat BioTech Ltd. Apart from these two vaccines, Sputnik V of Russia has been approved too, considering its high effectiveness. 

Will the vaccination help in stopping COVID-19 in our country?

People need to understand that while lockdowns might slow down the widespread, they are not a permanent fix. Getting vaccinated will alleviate the risk and complications of contracting the disease. This is the only way to win over the virus for once and all. Currently, only one per cent of our population has been vaccinated. So, it’s important that even after getting vaccinated, you follow the basic norms and precautions to save yourself and the people around you. 

#StayHome #StaySafe

COVID-19 Tips: What Should I Do If One Of My Family Members Becomes COVID-19 Positive?

With the country making a new record tally in the increasing number of COVID-19 cases every day, awareness and 100% precaution has become mandatory.

Every second household you’d know is suffering from coronavirus and no matter how much you try, there are chances that you or your family members could also get affected by it.

Here’s what you should do if one of your family members becomes COVID-19 positive!

Practice social distancing at home:

It is recommended to maintain social distancing at home in such cases. The COVID-19 patient is recommended to isolate him/ herself from the rest of the family.

A complete quarantine is advisable for the patient. From a separate room to a separate bathroom, if available, the COVID-19 patient must maintain zero contact with others.

Choose a room to follow quarantine:

The COVID-19 patient cannot just stay in any room. The room should be far from elders and children of the family and it should be well ventilated.

Even in the rest of your home, there should be enough flow of fresh air. The family members should wear a mask every time they are in contact with the patient or sharing a common space with them.

Use technology to communicate:

Try to stay away from the patient as much as possible, communicate via texts, calls or video chats. 

Keep a track of the patient’s help, his/ her heart rate and body temperature. Keep a tap of the ongoing condition — and if it improves or deteriorates.

Use separate products and daily essentials:

Apart from using a separate room and bathroom, it is also recommended to use separate household items and daily essentials like utensils, drinking glasses/ water bottles, cups/ dishes/ bowls, towels, bedcovers, etc.

Any item that cannot be disposed of immediately should be handled and shared with disposable gloves and washed with hot water and medicated soap. If there aren’t any gloves available in the house, wash your hands for 20 seconds every time you touch any item.

While disposing of any trash, use disposable gloves and wash your hands immediately after that.

Even the patient’s clothes should be washed separately in high-temperature water.

Avoid making contacts with pets:

The COVID-19 patient is recommended to make zero contact with any pet in the house. Family members who are coming in contact with the patient are also advised to wash their hands/ use sanitisers before touching their pets.

Monitor their health and symptoms:

You should keep a constant check on the patient’s health and symptoms. Stay in the loop with your concerned doctor and be prepared for any emergency.

While you keep a tap of their health, you must also keep a check on yourself and the rest of the family. 

Have proper food:

The COVID-19 patient should eat less spicy and healthy food. Include a lot of fruits, nuts and super seeds in their diet.

Also, ensure that the person stays hydrated throughout the day.

When to call for medical help?

If you notice any of the following symptoms on the COVID-19 patient, consider calling for immediate help:

  1. Bluish face or lips
  2. Inability to rouse
  3. Constant unavoidable pain in the chest
  4. Difficulty in breathing
  5. Any other kind of symptoms that you feel could be a warning sign

Some of the symptoms which a COVID-19 patient may or may not show are:

  1. Nausea/ vomiting
  2. Chills and fatigue
  3. Muscle and body pain
  4. Sore throat
  5. headache
  6. Runny nose/ cold
  7. Diarrhoea
  8. Congestion
  9. Other diseases like pneumonia and bronchitis

COVID-19 is real and it is not going to go so soon!

Although there will be a relief after the vaccination drive gets complete — it is still recommended to practice all the norms and safety precautions when any of your family members becomes COVID-19 positive.

  1. DO NOT come in direct contact with any of the COVID-19 patients.
  2. Always use a hand sanitiser with at least 60% of alcohol.
  3. Maintain proper hygiene and social distancing.
  4. Always wear a mask.
  5. Use disposable gloves.
  6. Keep a constant check on your’s and your loved ones’ health.

#StaySafe #StayHome

ALSO READ: Pregnancy In A Pandemic – What Are The Do’s & Don’ts?

Moderna planning to charge governments $25-$37 for its COVID-19 vaccine

https://www.financialexpress.com/lifestyle/health/moderna-to-charge-25-37-for-covid-19-vaccine-ceo/2133774/

Moderna’s CEO Stephane Bancel has announced that they are planning to charge $25-$37 (depending on the quantity ordered) for their Covid-19 vaccine. He was reportedly quoted saying “Our vaccine therefore costs about the same as a flu shot, which is between $10 and $50.”

 Moderna had earlier announced that it has developed a new vaccine for Covid-19 and the vaccine was 94.5% effective in preventing Covid-19 according to the preliminary data collected from a stage-3 clinical test.