Netherlands goalkeeper Mark Flekken was beaten on the stroke of halftime when Mueller latched onto a free ball in the box and thundered in his 43rd international goal.
The Netherlands were unlucky not to be given a penalty three minutes later when Germany’s Thilo Kehrer clearly felled Memphis Depay
Germany came close again in the final minutes through Lukas Nmecha but the 23-year-old could not snatch a late winner despite a golden chance.
The Netherlands came from a goal down to snatch a 1-1 draw against visitors Germany in their friendly international on Tuesday.