The moon lander Vikram, set on a GSLV Mark 3 heavy lift launch vehicle, is expect to land on the moon by August 23 after over 40 days of journey.
It will mark India's first landing in the South Pole of the moon.
ISRO has learned from the failures of its last moon mission in July 2019, reducing the number of engines on the lander from five to four and updating the software.
ISRO's new mission is designed to land successfully even if certain elements fail, having implemented measures to counter possible scenarios including sensor and engine failures.