The right-arm pacer made his List A debut for Goa in the Vijay Hazare Trophy in 2017. He then made his first-class debut for his state in the Ranji Trophy next year.
Prabhudessai made his Twenty20 debut for Goa in the Syed Mushtaq Ali Trophy in 2019.
He made his presence felt when he was involved in the run out of CSK all-rounder Moeen Ali with a quick throw to wicketkeeper Dinesh Karthik in their IPL 2022