Meera, 16-year-old daughter of actor and music director Vijay Antony, reportedly committed suicide at her Chennai home.
Her death was confirmed by film trade analyst Manobala Vijayabalan.
Vijay Antony's family and Meera's school friends will be questioned about her alleged suicide.
Earlier this year, Meera became the cultural secretary of her school students association.
She was under pressure and was receiving treatment.
Earlier this year, Vijay Antony underwent surgery due to an accident on the sets of his film Pichaikkaran 2 in Malaysia.