Know that your response to a mistake defines the audience’s response.
If you respond to spilling water on your pants as if it were the sinking of the Titanic, the audience and you will see it as a tragedy. But if you’re cool, or better yet, find it funny, the audience will do the same.
What The Audience Want
It’s often the case that the things speakers obsess about are the opposite of what the audience cares about. They want to be entertained. They want to learn. And most of all, they want you to do well.